COPD is a broad term that comprises several chronic (on-going) lung conditions such as chronic bronchitis* and emphysema**. Key signs and symptoms may include difficulty breathing/shortness of breath, wheezing, tiredness, and a chronic cough (with or without mucus). Symptoms may get worse at times, called “exacerbations.” These flare-ups may do further damage to the lungs, so it’s important to effectively treat COPD.
*Chronic bronchitis is due to damage to bronchial tubes. They become irritated and swollen resulting in coughing and shortness of breath. If there is mucus with the cough for at least several months, it’s considered “chronic” bronchitis.
**Emphysema is when the air sacs in the lungs become damaged and can no longer do a good job of taking the oxygen you breathe into your blood for other organs to use.
Though there is no cure for COPD, medications exist to help make breathing easier. Even so, more targeted treatments are needed and studies like this one are how we develop them.
The purpose of the ENDURA studies is to see if the investigational medicine can reduce the number of COPD flare-ups, called exacerbations, and help improve quality of life in people with the condition.
The ENDURA studies are each assessing the same investigational medication — a type of biologic medicine given as an injection under the skin — for the treatment of moderate to severe COPD. “Biologic” simply means that it is derived from a living thing (like cells) as opposed to being a synthetic chemical.
By “investigational,” we mean that it has not been approved for use by the general public but is currently being evaluated in these studies.
Total participation in the study will vary but will last about 1 to 2 years. Know that you can withdraw from a study at any time and for any reason.
Act now to see if you may qualify for an ENDURA study.